Aluminum honeycomb sandwich panel which can be an replacement of aluminum-plastic panel, it has excellent properties of high wind pressure resistance, shock absorption, sound insulation, heat preservation, flame retardant and high specific strength. The weight of honeycomb plate with the same stiffness is only 1 / 5 of that of aluminum veneer and 1 / 10 of that of steel plate. The building load and cost can be greatly reduced. Because the middle interlayer contains a large amount of air, it can be sound and heat insulated, has no combustible substances, has a fire rating of B1, is waterproof, moisture-proof, has no harmful gas release, and is not easy to deform.